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a-PVP (α-Pyrrolidinopentiophenone, alpha-pyrrolidinovalerophenone, α-PVP, alpha-PVP, O-2387, β-ketone-prolintane, prolintanone, or desmethylpyrovalerone) is psychomotor stimulant compound developed in the 1960s and related to pyrovalerone and is the ketone analog of prolintane. Pyrovalerone is an inhibitor of the transporters for certain monoamine neurotransmitters, including dopamine and norepinephrine, preventing their uptake.
a-PVP is a synthetic cathinone derivative and appears to act as a potent blocker at the dopamine and norepinephrine transporter and pre-clinical research into areas of abuse liability, psychomotor activity and drug discrimination suggests that the properties of α-PVP are reminiscent of MDPV, methamphetamine and cocaine.
SUBSTANCE IDENTIFICATION:
a-PVPÂ has formal name: (RS)-1-Phenyl-2-(1-pyrrolidinyl)-1-pentanone. The chemical formula for a-PVP is C15H21NO with a molecular weight of 231.339
EFFECT AND DOSAGE OF A-PVP:
The behavioral effects induced by a-PVP were observed to be comparable to other psychomotor stimulants such as cocaine, methamphetamine and MDPV.
TOXICOLOGY OF A-PVP:
The toxicity and long-term health effects of recreational a-PVP use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown.
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